Breast and Hereditary Ovary Cancer BRCA 1 and BRCA 2

Breast and Hereditary Ovary Cancer BRCA 1 and BRCA 2 2017-08-29T16:10:54-03:00

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Breast and Ovary Cancer are diseases which commonly affect women, but some of them are only hereditary ones. Hereditary cancer occurs when a mother or a father provides a genetic mutation of BRCA1 and BRCA2 to his/her offspring. Changes in genes suppose a 3 to 5 % of all breast cancer and up to a 15% of all ovary cancers. Mutations in these two genes also increase breast cancer risk in women and prostate cancer in men.

The complete sequence study of BRCA 1 and BRCA 2 genes search for mutations along these two genes. If a BRCA1 and BRCA2 test provides a positive result, this indicates that the person that went through the test has a high risk to have hereditary cancer. In these cases, there are some behaviors that may be taken to diminish this risk in you and your family.

Some questions that men and women suspected of a high risk to have BRCA1 and BRCA2 mutations should ask are the following:

 

female

  • Have you had breast cancer at 50 years old or before?
  • Have you had ovary cancer, fallopian tubes cancer or peritoneum cancer?
  • Have you had one or more relatives with breast cancer, ovary cancer, pancreas cancer or aggressive prostate cancer?
  • Do you belong to the Ashkenazi Jewish community and have had breast cancer?

male

  • Do you have at least one relative with a mutation in BRCA 1 and BRCA 2 genes?
  • Have you had breast cancer?
  • Have you had pancreas cancer or aggressive prostate cancer?
  • Do you have at least two relatives who have had breast cancer, ovary cancer, pancreas cancer or prostate cancer?
  • Do you have a family record on breast cancer and ovary cancer?

Learn more about other Hereditary Diseases

COMPLETE SEQUENCING STUDY OF BRCA 1 AND BRCA2

Developed with NEXT GENERATION SEQUENCING, maximum genetic sequencing technology available at a world level.

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BIOMAKERS is a pioneer institution and represents the unique laboratory that offers the complete sequencing study of BRCA 1 and BRCA2 fully developed in its facilities in Argentina.

This study is carried out by different scientific experts who integrate BIOMAKERS professional team, who has also developed an exclusive report of results, based on an extensive review of international database of mutations record, scientific publications and validated predictive models. All this information let us interpret every genetic sequence and to arrive to an acute result. Due to the fact that not all the results are associated to an increased risk of suffering from breast cancer or ovary cancer, BIOMAKERS provides a team of specialist’s molecular biologists and doctors who review every case in particular to provide personalized counseling to each patient or relative.

 

Statistics on Breast Cancer and Hereditary Ovary Cancer caused by BRCA 1 and BRCA 2 mutations

  • Produces 5 to 10% of all breast cancer cases and up to a 15% of all ovary cancers.
  • People with BRCA mutations have up to 85% of risk of developing breast cancer and up to a 40% of developing ovary cancer in some point in their lives.
  • The offspring of a person who has a BRCA mutation has a 50% of chances of acquiring the same mutation, and facing similar risks.
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How to prevent it?

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Knowing if there is a mutation in BRCA genes is a prevention method to diminish the risk of developing breast and ovary cancer in the patient and its family.

Because we know that every patient faces crucial decisions that impact in their lives and its family, it is our goal to clear all the doubts during genetic counseling.

Ask for Genetic Counseling
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